Transformative Science Our scientists see the impossible as a good place to start. We are Relentless At Vertex, we strike at the core of serious disease to change people's lives, and won't stop until we discover a cure. Featured contents RESEARCH Scientific innovation is at the core of everything we do. We pursue the science to transform serious diseases. Since 2000, Vertex has invested more than $11B into scientific innovation. Learn More UNDERSTANDING CYSTIC FIBROSIS Cystic fibrosis is a rare, life-shortening genetic disease caused by mutations of the cystic fibrosis transmembrane conductance regulator – or CFTR – gene. Learn More WORKING HERE At Vertex, we have some of the industry’s best and brightest people helping us achieve our mission of discovering transformative medicines to help people with serious diseases like cystic fibrosis. Join Our Team